武汉大学，教授、博士生导师 / Professor, Wuhan University.

教育部“新世纪人才计划”入选者/ New Century Excellent Talents in University (NCET) Chinese Ministry of Education.

学习经历 / Education

2000-2002：美国德州大学医学院， 炎症基因表达调控 博士后 / Postdoctoral fellow in University of Texas at Houston, USA.

1999-2000：美国贝勒医学院，生物化学 博士后 / Postdoctoral fellow in Baylor College of Medicne, USA.

1995-1998：武汉大学 病毒学 博士 / Ph.D. in Virology, Wuhan University, China.

1983-1987：武汉大学 病毒学 学士 / B.S. in Virology, Wuhan University, China.

工作经历 / Work Experience

2007-至今：入选教育部“新世纪人才计划”/ New Century Excellent Talents in University (NCET) Chinese Ministry of Education.

2005-2007：获湖北省杰出青年基金资助/ Supported by Hubei Provincial Foundation for Distinguished Youth Scholar.

2003-至今：病毒学国家重点实验室 /武汉大学生命科学学院，教授 / Professor, State Key Laboratory of Virology, Wuhan University, China.

1988-1994：武汉大学病毒研究所，助教，讲师 / Research assistant, Lecturer, Institute of Virology, Wuhan University.

学术兼职 / Committee and Broad Memberships

1. 湖北省生物工程学会常务理事 / Board member, Hubei Society for Biotechnology.

研究方向 / Research Interests

主要从事肝炎病毒，流感病毒感染导致基于环加氧酶（COX-2），氧化氮合成酶（iNOS）， 白介素（IL-32）途径的致炎机理和炎症反应通路研究。/ Pathogenesis and inflammatory pathway via cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS) and interleukin-32 (IL-32) after infection by human viruses including HBV, HCV and influenza virus.

近期代表性学术论文 / Selected Recent Publications

1. Li W, Liu Y, Mukhtar MM, Rasool ST, Gao YC, Gong R, Hao Q, Peng GQ, Chen YN, Wu JG, Zhu Y* (2008). Activation of interleukin-32 proinflammatory pathway in response to influenza A virus infection. PLoS ONE 3(4): e1985.

2. Rasool ST, Tang H, Wu J, Li W, Mukhtar MM, Zhang J, Mu Y, Xing HX, Wu J, Zhu Y* (2008). Increased level of IL-32 during human immunodeficiency virus infection suppresses HIV replication. Immunol Lett. May 15;117(2):161-167.

3. Liu M, Yang YB, Gu CF, Yue YP, Wu KK, Wu JG, Zhu Y* (2007). Spike protein of SARS-CoV stimulates cyclooxygenase-2 expression via both calcium-dependent and calcium-independent protein kinase C pathways. FASEB J 21(7):1586-1596.

4. Liu M, Gu CF, Wu JG, Zhu Y* (2006). Amino acids 1 to 422 of the spike protein of SARS associated coronavirus are required for induction of cyclooxygenase-2. Virus Genes 33(3):309-317.

5. Zhu Y, Saunders MA, Yeh H, Deng W, Wu KK (2002). Dynamic regulation of cyclooxygenase-2 promoter activity by isoforms of CCAAT/ehancer binding proteins. J Biol Chem 277(9):6923-6928.

6. Schroer K#, Zhu Y# (# co-first author), Saunders MA, Deng WG, Xu XM, Meyer-Kirchrath J, Wu KK (2002). Obligatory role of cyclic adenosine monophosphate response element in cyclooxygenase-2 promoter induction and feedback regulation by inflammatory mediators. Circulation 105(23):2760-2765.