学习经历 / Education

1998-2000：中国科学院生物物理研究所 生物化学 博士后 / Postdoctoral Associate in Biochemistry, Institute of Biophysics, the Chinese Academy of Sciences, China.

1995-1998：武汉大学 生物物理化学 博士 / Ph.D. in Biophysical Chemistry, Wuhan University, China.

1985-1988：武汉大学 生物物理化学 硕士 / M.S. in Biophysical Chemistry, Wuhan University, China.

1981-1985：武汉大学 学士 / B.S., Wuhan University, China.


工作经历 / Work Experience

2001-至今：武汉大学，教授 / Professor, Wuhan University, Wuhan, China.

2001-2002：法国Louis Pasteur大学药理学与物理化学国家重点实验室，访问教授 / Invited Professor, CNRS, Université Louis Pasteur, France.

2006-2007：美国国立健康研究院生物化学与遗传学实验室，访问教授 / Invited Professor, NIDDK, National Institutes of Health, USA.


学术兼职 / Committee and Broad Memberships

1. 中国生物化学与分子生物学会蛋白质专业委员会委员 / Committee Member, Chinese Society of Biochemistry and Molecular Biology-Protein branch (Chinese Protein Society)

2. 中国生物化学与分子生物学会酶学专业委员会委员 / Committee Member, Chinese Society of Biochemistry and Molecular Biology-Enzymology branch

3. 《生物化学与生物物理学报》编委会成员/ Member of the editorial board of Acta Biochimica et Biophysica Sinica (ABBS).

近期代表性学术论文 / Selected Recent Publications

1 Zhou BR, Zhou Z, Hu QL, Chen J, Liang Y* (2008). Mixed macromolecular crowding inhibits amyloid formation of hen egg white lysozyme. Biochim Biophys Acta 1784(3): 472-480.

2. Du F, Zhou Z, Mo ZY, Shi JZ, Chen J, Liang Y* (2006). Mixed macromolecular crowding accelerates the refolding of rabbit muscle creatine kinase: implications for protein folding in physiological environments. J Mol Biol 364: 469-482.

3. Yang F Jr, Zhang M, Zhou BR, Chen J, Liang Y* (2006). Oleic acid inhibits amyloid formation of the intermediate of ?-lactalbumin at moderately acidic pH. J Mol Biol 362: 821-834.

4. Zhou YL, Liao JM, Chen J, Liang Y* (2006). Macromolecular crowding enhances the binding of superoxide dismutase to xanthine oxidase: Implications for protein-protein interactions in intracellular environments. Int J Biochem Cell Biol 38: 1986-1994.

5. Yang F Jr, Zhang M, Chen J, Liang Y* (2006). Structural changes of ?-lactalbumin induced by low pH and oleic acid. Biochim Biophys Acta 1764(8): 1389-1396.

6. Chen N, Fan JB, Xiang J, Chen J, Liang Y* (2006). Enzymatic hydrolysis of microcrystalline cellulose in reverse micelles. Biochim Biophys Acta 1764(6): 1029-1035.

7. Xu H, Liang Y*, Zhang P, Du F, Zhou BR, Wu J, Liu JH, Liu ZG, Ji LN (2005). Biophysical studies of a ruthenium(II) polypyridyl complex binding to DNA and RNA prove that nucleic acid structure has significant effects on binding behaviors. J Biol Inorg Chem 10(5): 529-538.

8. Wu J, Du F, Zhang P, Khan IA, Chen J, Liang Y* (2005). Thermodynamics of the interaction of aluminum ions with DNA: implications for the biological function of aluminum. J Inorg Biochem 99(5): 1145-1154.

9. Zhou BR, Liang Y*, Du F, Zhou Z, Chen J (2004). Mixed macromolecular crowding accelerates the oxidative refolding of reduced, denatured lysozyme: implications for protein folding in intracellular environments. J Biol Chem 279: 55109-55116.

10. Liang Y*, Du F, Sanglier S, Zhou BR, Xia Y, Van Dorsselaer A, Maechling C, Kilhoffer MC, Haiech J (2003). Unfolding of rabbit muscle creatine kinase induced by acid. A study using electrospray ionization mass spectrometry, isothermal titration calorimetry, and fluorescence spectroscopy. J Biol Chem 278(32): 30098-30105.