学习经历 / Education
1994-1998：荷兰农业大学 病毒学 博士 / Ph.D. in Virology, Wageningen Agricultural University, the Netherlands;
1986-1989：中科院武汉病毒研究所 病毒学 硕士 / M.S. in Virology, Wuhan Institute of Virology, Chinese Academy of Sciences,
1982-1986：武汉大学 病毒学 学士 / B.S. in Virology, Wuhan University, China..
工作经历 / Work Experience
2000-至今：中国科学院武汉病毒研究所，所长/ Director, Wuhan Institute of Virology, Chinese Academy of Sciences,
1999-2000：中国科学院武汉病毒研究所，副所长/ Deputy Director, Wuhan Institute of Virology, Chinese Academy of Sciences,
1997-至今：中国科学院武汉病毒研究所，研究员/ Professor, Wuhan Institute of Virology, Chinese Academy of Sciences,
1994-1997：中国科学院武汉病毒研究所，副研究员/ Associate professor, Wuhan Institute of Virology, Chinese Academy of Sciences,
1992-1994：中国科学院武汉病毒研究所，助理研究员/ Assistant professor ，Wuhan Institute of Virology, Chinese Academy of Sciences,
1993-1998 荷兰农业大学，访问学者/Visiting scientist; Department of Virology, Wageningen Agricultural University，the Netherlands,
2001 加拿大大湖森林研究中心，访问学者/ Laboratory for molecular Virology, Great Lakes Forest Research Center, Canada.
学术兼职 / Committee and Broad Memberships
1. 国际无脊椎病理学会理事/Trustee , the Society for Invertebrate Pathology.
2. 病毒学国家重点实验室学术委员会副主任 / Deputy Director, Broad Committee of the State Key Laboratory of Virology, China.
3. 农业部农业生物基因工程安全委员会委员/ Broad Member, the Safe of Agricultural Biological Gene Engineering committee of Ministry of Agriculture.
4. 中国科学技术协会常务委员 / Broad Member, Association for Science and Technology of China.
5. 湖北省微生物学会常务理事、学术委员会主任 / Broad Member, Hubei Society for Microbiology; Director, Academic Board.
6. 中国微生物学会病毒专业委员会委员 / Broad Member, Division of Virology of Chinese Society for Microbiology.
7. 《科学通报》、《国际病毒学杂志》、《中国病毒学》、《病毒学报》、《微生物与感染》、《昆虫学报》及《中国生物防治》编委/ Editorial Board Member，Chin Sci Bull，Interational Journal of Virology，Virologica Sinica，Chinese Journal of Virology，Journal of Microbes and Infection，Acta Entomologica Sinica and Biotic-control of China.
研究方向 / Research Interests
利用分子生物学和基因组学研究手段，研究病毒的感染机理、病毒与宿主的相互作用；发展杆状病毒表达系统和病毒检测技术；同时开展新生病毒疾病的分子生物学和流行病学研究。目前研究对象有杆状病毒、SARS冠状病毒和克里米亚-刚果出血热病毒等。
The main research fields of the Research Group of Functional Genomics and Genetic Engineering of Viruses include: infection mechanisms of viruses; virus-host interaction; functional genomics of viruses; molecular biology and epidemiology of emerging viruses; as well as development and applications of baculoviral expression system and viral diagnostic techniques. The recent research targets include baculovirus, SARS-CoV and Crimean-Congo hemorrhagic fever virus.
近期代表性学术论文 / Selected Recent Publications
1. Huang J., B. Hao, F. Deng, X. Sun, H. Wang, Z. Hu*. 2008. The open reading frame Bm21 of Bombyx mori nucleopolyhedrovirus is not essential for the viral replication in vitro but its deletion extends the median survival time of the infected larvae. Journal of General Virology 89, : 922-930. (SCI, IF: 3.11, Top 30%)
2. Z. Shi and Z. Hu*. 2008. A review of studies on animal reservoirs of the SARS coronavirus. Virus Research, 133(1):74-87. (SCI, IF: 2.783)
3. Deng F., R. Wang , M. Fang, Y. Jiang, X. Xu, H. Wang, X. Chen, B. M. Arif, L. Guo, H. Wang, Z. Hu*. 2007. Proteomics analysis of HearNPV identified two new ODV associated proteins, HA44 and HA100. Journal of Virology 81, 9377-9385. (SCI, IF: 5.341, Top 15%)
2. Dong C., F. Deng, D. Li, H. Wang, Z. Hu*. 2007. The heptad repeats region is essential for AcMNPV P10 filament formation and not the proline-rich or the C-terminus basic regions. Virology 365, 390-397. (SCI, IF: 3.525, Top 30%)
4. Liu L., Q. Fang, F. Deng, H. Wang, C. E. Yi, L. Ba, W. Yu, R. D. Lin, T. Li, Z. Hu, D. D. Ho, L. Zhang, and Z. Chen*. 2007. Natural Mutations in the receptor binding domain of spike glycoprotein determine the reactivity of cross-neutralization between palm civet coronavirus and severe acute respiratory syndrome coronavirus. Journal of Virology, 81, 4697-4700. (SCI, IF: 5.341, Top 15%)
5. Pan X., G. Long, R. Wang, S. Hou, H. Wang, Y. Zheng, X. Sun, M. Westenberg, F. Deng, H. Wang, J. M. Vlak and Z. Hu*. 2007. Deletion of a Helicoverpa armigera nucleopolyhedrovirus gene encoding a virion structural protein (ORF107) increases the BV titre and reduces in vivo infectivity. Journal of General Virology 88, 3307-3316 . (SCI, IF: 3.11, Top 30%)
6. Fang M., Y. Nie, Q. Wang, F. Deng, R. Wang, H. Wang, H. Wang, J. M. Vlak, X. Chen and Z. Hu*. 2006. Open reading frame 132 of Heliocoverpa armigera nucleopoly-hedrovirus encodes a functional per os infectivity factor (pif-2). Journal of General Virology 87, 2563-2569. (SCI, IF: 3.11, Top 30%)
7. Dong C, D. Li, G. Long, F. Deng, H. Wang and Z. Hu*. 2005. Identification of functional domains of HearNPV P10 for filament formation. Virology 338, 112-120. (SCI, IF: 3.525, Top 30%)
8. D. Wu, F. Deng, X. Sun, H. Wang, L. Yuan, J. M. Vlak, Z. Hu*. 2005. Functional analysis of FP25K of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus. Journal of General Virology, 86: 2439-2444. (SCI, IF: 3.11, Top 30%)
9. J. A. Jehle, M. Lange, H. Wang, Z. Hu, Y. Wang, R. Hauschilda. 2005. 2005-2006 Molecular identif ication and phylogentic analysis of baculoviruses from Lepidoptera. Virology, accepted . (SCI, IF: 3.525, Top 30%)
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