学习经历 / Education
2002-2004：武汉大学 生物学 博士后 / Postdoctoral Associate in Biology, Wuhan University, China.
1999-2002：武汉大学 分析化学 博士 / Ph.D. in Analytical Chemistry, Wuhan University, China
1996-1999：南昌大学 分析化学 硕士 / M.S. in Analytical Chemistry, Nanchang University, China.
1992-1996：南昌大学 分析化学 学士 / B.S. in Analytical Chemistry, Nanchang University, China.
工作经历 / Work Experience
2004-至今：武汉大学，副教授/Associate Professor, Wuhan University, Wuhan, China
研究方向 / Research Interests
1． 蝎毒肽结构功能研究及药物研发/ Structure-function research of scorpion toxin peptides and drug development
2． 病毒与宿主细胞的膜融合机制研究 / Focus on the membrane fusion mechanisms between virus and host cells.
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近期代表性学术论文 / Selected Recent Publications
1. Song Han, Hong Yi, Shi-Jin Yin, Zong-Yun Chen, Hui Liu, Zhi-Jian Cao, Ying-Liang Wu*, Wen-Xin Li. Structural basis of a potent peptide inhibitor designed for Kv1.3 channel, a therapeutic target of autoimmune disease. J.Bio.Chem. 2008-in press
2. Yi H, Qiu S, Cao ZJ, Wu YL*, Li WX. Molecular basis of inhibitory peptide maurotoxin recognizing Kv1.2 channel explored by ZDOCK and molecular dynamic simulations. PROTEINS: Structure, Function, and Bioinformatics. 2008 80:744-54.
3. Wu YL, Yi H, Cao ZJ, Li WX. Conformation of Trimeric Envelope Glycoproteins: The CD4-dependent Membrane Fusion Mechanism of HIV-1. J Biomol.Struct.Dyn. 2007, 25(1):1-9.
4. Yi H, Cao ZJ, Yin SJ, Dai C, Wu YL*, Li WX*. Interaction Simulation of hERG K+ Channel with its specific Bekm-1 peptide: Insights into the Selectivity of Molecular Recognition. J.Proteome.Res. 2007, 6(2): 611-20.
5. Ling Jin, and Yingliang Wu*, Molecular Mechanism of the Sea Anemone Toxin ShK Recognizing the Kv1.3 Channel Explored by Docking and Molecular Dynamic Simulations. J. Chem. Inf. Model., 2007, 47(5): 1967-1972
6. Sha YG, Wu YL, Cao ZJ, Xu XL, Wu WL, Jiang DH, Mao X, Liu H, Li WX. A convenient cell fusion assay for the study of SARS-CoV entry and inhibition. IUBMB Life, 2006, 58(8):480-6.
7. Mouhat, S; Teodorescu, G; Homerick, D; Visan, V; Wulff, H; Wu, YL; Grissmer, S; Darbon, H; De Waard, M; Sabatier, JM. Pharmacological profiling of Orthochirus scrobiculosus toxin 1 analogs with a trimmed N-terminal domain. Molcecular Pharmacology, 2006, 69 (1): 354-362
8. Yingliang Wu, Zhijian Cao, Hong Yi, Dahe Jiang, Xin Mao, Hui Liu, Wenxin Li. Simulation of the Interaction between ScyTx and small conductance calcium-activated potassium channel by docking and MM-PBSA. Biophy.J. 2004, 87: 105-112.
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