病毒学国家重点实验室，教授/ Professor, State Key Laboratory of Virology.

武汉大学医学院分子病毒与癌研究室，主任/ Director, Lab of Molecular Virology &Cancer, Wuhan University Schoole of Medicine.

武汉大学，教授、博士生导师 / Professor, Wuhan University.

学习经历 / Education

1987-1988：武汉大学师资培训中心 英语 学员 / Student, in English, Visiting Scholar training, Wuhan University, China.

1979-1982：武汉大学医学院 医学病毒学 硕士生 / M.S. in Virology, Wuhan University, China.

1973-1975：武汉大学医学院 临床医学 学生 / B.S. in Clinic Medicine, Wuhan University School of Medicine, China.

1972-1973: 天津大学医学院 肿瘤学 进修生 / Visiting Scholar, in Oncology, Tianjing University School of Medicine, China.

1971-1972：武汉大学医学院卫生班 临床医学 学生/ Student, in Clinic Medicine, Training Team of Hygiene, Wuhan University School of Medicine, China.


工作经历 / Work Experience

2005-至今：病毒学国家重点实验室，教授 / Professor, State Key Laboratory of Virology, China.

1994-至今：武汉大学医学院分子病毒与癌研究室, 主任 / Director, Lab of Molecular Virology &Cancer, Wuhan University Schoole of Medicine, China.

1998-至今：武汉大学，教授 / Professor, Wuhan University Schoole of Medicine, China.

1994-1998：武汉大学，副教授 / Associate Professor, Wuhan University Schoole of Medicine, China.

1993-1994：中国科学院武汉病毒研究所，副研究员 / Research Associate Professor, Wuhan Institute of Virology, Chinese Academy of Sciences, China

Sept-Dec, 1990：美国夏威夷大学 微生物学 访问 / Visiting Scholar, in Microbiology, Hawaii University, USA.

1996-1993：中国科学院武汉病毒研究所，助理研究员 / Research Assistant Professor, Wuhan Institute of Virology, Chinese Academy of Sciences, China

1982-1996：中国科学院武汉病毒研究所，实习研究员 / Research Assistant, Wuhan Institute of Virology, Chinese Academy of Sciences, China

1975-1982：武汉大学中南医院肿瘤科 医生 / Doctor, Oncology Department of Zhongnan Hospital, Wuhan University Schoole of Medicine, China.

学术兼职 / Committee and Broad Memberships

1. 武汉理工大学 生物材料学科 兼职博士生导师 / Pluralist Professor, Wuhan University of Technology, China.

2. 武汉大学ABSL-3实验室 专家 / specialist, ABSL-3 Lab of Wuhan University, China.

3. 湖北省生物工程学会 副理事长 / Vice-President, Hubei Society for Biotechnology, Hubei Province, China.

4. 湖北省预防医学会 理事 / Board Member, Hubei Council of Preventive Medicine, China.

5. 湖北省暨武汉市分析微生物学会 副主任委员（创始人）/ Vice-Director, the Society of Hubei & Wuhan for Analysis Microbiology(a Founder), China.

近期代表性学术论文 / Selected Recent Publications

1. J Hu, CY Dong, Joseph Li, J Chen, DE Chen, K Liang ,WY Zhang(2008). In vitro Selective cytotoxic effect of human cancer cells by Bluetongue virus-10. Acta Oncologica 47:124-134.

2. F CHEN, Z TAN, CY DONG(2007). Combination of VEGF165/Angiopoieitn-1 gene and endothelial progenitor cells for therpeutic neovascualrization. European Journal of Pharmacology 568: 222-230.

3. Feng CHEN, Zui TAN, Chang-yuan DONG, Xiao CHEN, Shu-fang GUO(2007). Adeno-associated virus vectors simultaneously encoding VEGF and angiopoietin-1 enhances neovascularization in ischemic rabbit hindlimbs. Acta Pharmacol Sin 28 (4): 493–502.

4. Feng Xue, Chang-yuan Dong, Yue Su, Huabin Zhu, Weifang Ling, Yingle Liu, Hua Xu, Wei Xiao, Shumin Zhou, Yi-peng Qi(2005). Tumor-Targeted Therapy with a Conditionally Replicating Mutant of HSV-1 Induces Regrssion of Xenografted Human Hepatomas. Cancer Biology & Therapy 4(11): 24-29.

5. Chen Minhui, Dong Changyuan, Liu Zhihui, GRB Skinner, CE Hartley(1983). Prevention of type 2 herpes simplex virus induced cervical carcinoma in mice by prior immunization with a vaccine prepared from type 1 herpes simplex virus. Vaccine 1(1): 13-16.

6. Cao Xianying, Li Shipu, Dai Honglian, Dong Changyuan(2005). The effect of nano-apatite on the expression of telomerase gene of human hepatocellular carcinoma cells. Journal of Wuhan University of Technology (Materials Sci Ed) 20: 315-317.

7. Yin-Fang Yan, Xiao Chen, Ying Zhu, Jian-Guo Wu, Chang-Yuan Dong(2005). Selective Cytolysis of Tumor Cells by Mumps Virus S79. Intervirology 48: 292-296.

8. Xue Feng, Joshua Mallam Nock, Zhu Hua-bin, Dong Chang-yuan, Qi Yi-peng(2004). Construction and in vitro study of an E1B-defective adenovirus. Wuhan University Journal of Natural Sciences 9（2）: 259-264.

9. Baoli Hu, Mallam Nock Joshua, Changyuan Dong, Yipeng Qi(2004). Development of a novel recombinant adenovirus containing gfp –zeocin fusion expression cassette for conditional replication in p53 deficient human tumor cells. Journal of Virological Methods 117:129-136.

10. Ping Lan, Changyuan Dong, Yipeng Qi, Gengfu Xiao, and Feng Xue(2003). Gene therapy for mice sarcoma with oncolytic herpes simplex virus-1 lacking the apoptosis-inhibiting gene, icp34.5. Journal of Biochemistry and Molecular Biology 36(4): 379-386.

11. Feng Xue, Yipeng Qi, Mallam Nock Joshua, Ping Lan, Changyuan Dong(2003). Conditional replication of a recombinant adenovirus studied using neomycin as selective marker. Journal of Biochemistry and Molecular Biology 36(3): 275-281.