学习经历 / Education
2000-2003：Staatliche- Lehr Und Forshungs Anstalt, RLP, Germany (DAAD);
Wageningen University, Holland (Nuffic);Sandwich-PH.D progremmes
2000-2003：中科院水生所 分子遗传学 博士 / Ph.D. in Molecular Genetics, CAS, China.
1997-2000：中科院武汉病毒所 病毒学 硕士 / M.S. in Virology, Wuhan Institute of Virology, CAS, China.
1992-1997：复旦大学 微生物学及微生物工程 学士 / B.S., Fudan University, China.
工作经历 / Work Experience
2007-至今：中科院武汉病毒所，研究员 / Professor, CAS, China.
2002-2007：中科院武汉病毒所，副研究员 / Associate Professor, CAS, China.
2005-至今：湖北省病毒疾病工程技术研究中心，常务副主任 / Deputy director, Viral disease engineering and technological research centre of Hubei province, China.
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近期代表性学术论文 / Selected Recent Publications
1. Tan Y, Jiang L, Wang ML, Yin F, Deng F, Liu M, Hu Z, and Wang HL* (2008) Mutagenesis and NMR analyses of fusion peptide of the Helicoverpa armigera Single Nucleocapsid Nucleopolyhedrovirus F protein. J. Virol.
2. Yin F, Wang ML, Tan Y, Deng F, Vlak JM, Hu Z and Wang HL* (2008) functional F analogue of AcMNPV GP64 from the Agrotis segetum Granulovirus. J. Virol.
3. Wang, M., Y. Tan, F. Yin, F. Deng, J. M. Vlak, Z. Hu, and Wang HL* (2008) The F protein of Helicoverpa armigera single nucleopolyhedrovirus can be substituted functionally with its homologue from Spodoptera exigua multiple nucleopolyhedrovirus. J. Gen. Virol. 89:791-798.
4. Xu, J., J. Wang, F. Deng, Z. Hu and Wang HL* (2008) Green tea extract and its major component epigallocatechin gallate inhibits hepatitis B virus in vitro. Antiviral Res. 2008 Feb 8 [Epub ahead of print] PMID: 18313149.
5. Deng F., R. Wang, M. Fang, Y. Jiang, X. Xu, H. Wang, X. Chen, B. M. Arif, L. Guo, Wang HL, Z. Hu. (2007) Proteomics analysis of HearNPV identified two new ODV associated proteins, HA44 and HA100. J Virol, 81, 9377-9385.
6. Dong C., F. Deng, D. Li, Wang HL, Z. Hu (2007) The heptad repeats region is essential for AcMNPV P10 filament formation and not the proline-rich or the C-terminus basic regions. Virology.365,390-397 (2007).
7. Xu J, Wang HL, Fan J (2007) Expression of a ribosome-inactivating protein gene in bitter melon is induced by Sphaerotheca fuliginea and abiotic stimuli. Biotechnol Lett 29:1605–1610.
8. G. Long, M. Westenberg, Wang HL, J.M. Vlak and Z. Hu (2006) Function, oligomerization and N-linked glycosylation of the Helicoverpa armigera single nucleopolyhedrovirus envelope fusion protein. J. Gen. Virol, 87,839-846.
9. Wang HL, D. Wu, F. Deng, H. Peng, X. Chen, H. Lauzon, B. M. Arif, J. A. Jehle and Z. Hu (2004). Characterization and phylogenetic analysis of the chitinase gene from the Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus. Virus Research 100，179-189.
10. Westenberg M, Wang HL, IJkel WF, Goldbach RW, Vlak JM, Zuidema D (2002) Furin is involved in baculovirus envelope fusion protein activation. J Virol. 76(1):178-84.
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