病毒学国家重点实验室，副主任 / Associate Director, State Key Laboratory of Virology.
教育部“新世纪优秀人才支持计划”入选者 / The gainer of Program for New Century Excellent Talents in University( NCET), Ministry of Education.
武汉大学，教授、博士生导师 / Professor, Wuhan University.
学习经历 / Education
1995-1998：武汉大学 病毒学 博士 / Ph.D. in Virology, Wuhan University, China.
1989-1992：同济医科大学 微生物学 硕士 / M.S. in Microbiology, Tongji Medical University, China.
1984-1989：同济医科大学 医学 学士 / B.S. in Medicine, Tongji Medical University, China.
工作经历 / Work Experience
2007-至今：病毒学国家重点实验室，副主任 /Associate Director, State Key Laboratory of Virology, China.
2005-至今：武汉大学，教授 / Professor, Wuhan University, China.
2001-2005：武汉大学，副教授 /Associate Professor, Wuhan University, China.
1994-2001：武汉大学，讲师 / Lecture, Wuhan University, China
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近期代表性学术论文 / Selected Recent Publications
1. Guo M, Huang T, Cui Y, Pan B, Shen A, Sun Y, Yi Y, Wang Y, Xiao G*, Sun G*(2008). PrPC interacts with tetraspanin-7 through bovine PrP154-182 containing alpha- helix 1.Biochem Biophys Res Commun. 365(1):154-157.
2. Peng X, Pan J, Gong R, Liu Y, Kang S, Feng H, Qiu G, Guo D, Tien P, Xiao G*(2007). Functional characterization of syncytin-A, a newly murine endogenous virus envelope protein. Implication for its fusion mechanism. J Biol Chem. 282(1):381-389.
3. Gong R, Huang L, Shi J, Luo K, Qiu G, Feng H, Tien P, Xiao G*(2007). Syncytin-A mediates the formation of syncytiotrophoblast involved in mouse placental development. Cell Physiol Biochem. 517-526.
4. Yu S, Zhang Y, Li S, Sy MS, Sun S, Tien P, Xiao G*(2007). Early onset fatal familial insomnia with rapid progression in a Chinese family line. J Neurol. 254(9):1300-1301.
5. Yin S, Yu S, Li C, Wong P, Chang B, Xiao F, Kang SC, Yan H, Xiao G, Grassi J, Tien P, Sy MS*(2006). Prion proteins with insertion mutations have altered N-terminal conformation and increased ligand binding activity and are more susceptible to oxidative attack. J Biol Chem. 281(16):10698-10705.
6. Sun G, Guo M, Shen A, Mei F, Peng X, Gong R, Guo D, Wu J, Tien P, Xiao G*(2005). Bovine PrPC directly interacts with alpha B-crystalline. FEBS Lett. 579(24):5419-5424.
7. Gong R, Peng X, Kang S, Feng H, Huang J, Zhang W, Lin D, Tien P*, Xiao G*(2005).Structural characterization of the fusion core in syncytin, envelope protein of human endogenous retrovirus family W. Biochem Biophys Res Commun. 331(4):1193-1200.
8. Yu SL, Jin L, Sy MS, Mei FH, Kang SL, Sun GH, Tien P, Wang FS*, Xiao GF*(2004). Polymorphisms of the PRNP gene in Chinese populations and the identification of a novel insertion mutation. Eur J Hum Genet. 12(10):867-870.
9. Liu S, Xiao G, Chen Y, He Y, Niu J, Escalante CR, Xiong H, Farmar J, Debnath AK, Tien P, Jiang S* (2004). Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors. Lancet. 363(9413):938-947.
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