郑春福研究员，博导、“百人计划”入选者 |
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中国科学院“百人计划”入选者 / Professor of “the Hundred Talents Program” of The Chinese Academy of Sciences
病毒学国家重点实验室，成员 / Member, State Key Laboratory of Virology, China
中国科学院武汉病毒研究所，研究员、博士生导师 / Professor/Senior Scientist, Wuhan Institute of Virology, Chinese Academy of Sciences.
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学习经历 / Education
2005-2007：加拿大卡尔加里大学 分子免疫学 博士后 / Postdoctoral Research Scientist in Molecular Immunology, University of Calgary, Canada.
2001-2005：加拿大萨斯喀彻温大学 分子病毒学 博士后/ Postdoctoral Research Scientist in Molecular Virology, University of Saskatchewan, Canada.
1998-2001：重庆医科大学 医学 博士/ Ph.D. in Medicine, Chongqing Medical University, China.
1994-1997：福建医科大学 医学 硕士 / M.S. in Medicine, Fujian Medical University, China
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1987-1991：中国农业大学 兽医学 学士/ B.S. in Veterinary Medicine, China Agriculture University, China.
工作经历 / Work Experience
2007-至今：中国科学院“百人计划”入选者 / Professor of “ the Hundred talents Program” of The Chinese Academy of Sciences
2007-至今：病毒学国家重点实验室，成员 / Member, State Key Laboratory of Virology, China
2007-至今：中国科学院武汉病毒研究所，研究员 / Professor/Senior Scientist, Wuhan Institute of Virology, Chinese Academy of Sciences, China.
1997-1998：福建医科大学基础医学院，助教 / Teaching Assistant, College of Basic Medicine,Fujian Medical University, China
1991-1994：福建省计划生育研究所灵长类实验研究中心，兽医/ Veterinary, The Primate Experimental Center, Fujian Institute of Family Planning, China
学术兼职 / Committee and Broad Memberships
湖北省细胞生物学学会理事/ Broad Member, Hubei Society for Cell Biology
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研究方向 / Research Interests
主要从事病毒（疱疹病毒、HIV和HCV等）分子生物学以及病毒免疫学的研究。具体研究内容包括病毒核膜穿梭机制，病毒与宿主细胞相互作用，抗病毒疫苗的研制，新的诊断及治疗方法的探索，以及病毒免疫逃避和致病机理的研究。/ The research interest of our group focuses on the molecular biology of viral proteins and immunology. We are particularly interested in the following areas: Molecular mechanisms of viral nuclear transport, interaction between virus and cells, new approaches to the prevention and treatment of infectious diseases, pathogenesis, immune evasion, caused by important virus including HSV, HCV, HIV.
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近期代表性学术论文 / Selected Recent Publications
1. Zheng CF, Jones GJ, et al. 2008 Late Expression of Granulysin by Microbicidal CD4+ T Cells Requires PI3K and STAT5-dependent Expression of IL-2R? that is Defective in HIV-infected Patients. Journal of Immunology. In press.
2. Zheng CF, Ma LL, Jones GJ, et al. (2007). Cytotoxic CD4 (+) T cells use granulysin to kill Cryptococcus neoformans, and activation of this pathway is defective in HIV patients . Blood 109(5): 2049-2057 .
3. Zheng CF, Babiuk LA, Littel-Van Den Hurk SV (2005). Bovine herpesvirus 1 VP22 enhances the efficacy of a DNA vaccine in cattle. Journal of virology 79(3): 1948-1953.
4. Zheng CF, Brownlie R, Babiuk LA, et al. (2005). Characterization of the nuclear localization and nuclear export signals of bovine herpesvirus 1 VP22. Journal of virology 79(18): 11864-11872.
5. Zheng CF, Brownlie R, Babiuk LA, et al. (2004). Characterization of nuclear localization and export signals of the major tegument protein VP8 of bovine herpesvirus-l. Virology 324(2): 327-339.
6. Zheng CF, Juhls C, Oswald D, et al. (2006). Effect of different nuclear localization sequences on the immune responses induced by a MIDGE vector encoding bovine herpesvirus-1 glycoprotein D. Vaccine 24(21): 4625-4629.
7. Zheng CF, Brownlie R, Huang DY, et al. (2006). Intercellular trafficking of the major tegument protein VP22 of bovine herpesvirus-1 and its application to improve a DNA vaccine. Archives of Virology 151(5): 985-993.
8. Zheng CF, Xie PM, Chen YT (2003). Molecular cloning and sequencing of the merozoite surface antigen 2 gene from Plasmodium falciparum strain FCC-1/HN and expression of the gene in mycobacterial. Journal of Eukaryotic Microbiology 50(2):140-143.
9. Zheng CF, Xie PM, Chen YT (2002). Recombinant Mycobacterium bovis BCG producing the circumsporozoite protein of Plasmodium falciparum FCC-1/HN strain induces strong immune responses in BALB/c mice. Parasitology International 51: 1-7.
10. Zheng CF, Xie PM, Chen YT (2001). Immune response induced by recombinant BCG expressing merozoite surface antigen 2 from Plasmodium falciparum. Vaccine 20(5-6): 914-919.
11. Zheng CF, Xie PM, Chen YT (2001). Molecular cloning and sequencing of the circumsporozoite protein gene from Plasmodium falciparum strain FCC-1/HN and expression of the gene in mycobacteria. Journal of Clinical Microbiology 39(8): 2911-2915.
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联系方式 / Contact Information
电话 / Tel: 86-27-87198676 (O); 86-27-87198286 (Lab); 传真 / Fax: 86-27-87198676
电子邮箱 / E-mail: zhengcf@wh.iov.cn
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